Assoc.Prof.Dr. Pakit Kumboonma

ตำแหน่งทางวิชาการ : รองศาสตราจารย์

ตำแหน่งบริหาร

• 2562-ปัจจุบัน ตำแหน่งผู้ช่วยคณบดีด้านพัฒนานักศึกษา คณะวิทยาศาสตร์และศิลปศาสตร์

ทักษะความชำนาญ

• เคมีอินทรีย์
• สารผลิตภัณฑ์ธรรมชาติ
• เคมีอินทรีย์สังเคราะห์
• เคมีสีเขียว

ผลงานทางวิชาการ

• Teerapongpisan, P., Suthiphasilp, V., Kumboonma, P., Maneerat, T., Duangyod, T., Charoensup, R., Andersen, R.j., Laphookhieo, S. Phaeanthuslucidines A-D, dimeric aporphine alkaloid derivatives from Phaeanthus lucidus Oliv. Phytochemistry 2023; 212: 113717.
• Somsakeesit, L., Joompang, A., Phosri, S., Srikoon, P., Kumboonma, P., Senawong, T., Phaosiri, C. Evaluation of histone deacetylase inhibitory and antiproliferative activity of piperine and its derivatives. Songklanakarin J. Sci. Technol. 2022; 44(6): 1481-1488.
• Suthiphasilp, V., Rujanapun, N., Kumboonma, P., Chaiyosang, B., Tontapha, S., Maneerat, T., Patrick, B.O., Andersen, R.J., Duangyod, T., Charoensup, R., Laphookhieo, S. Antidiabetic and cytotoxic activities of rotenoids and isoflavonoids isolated from Millettia pachycarpa Benth. ACS Omega 2022; 7: 24511−24521.
• Namwan, N., Senawong, G., Phaosiri, C., Kumboonma, P., Somsakeesit, L., Leerat, C., Senawong, T. HDAC inhibitory and anti-cancer activities of curcumin and curcumin derivative CU17 against human lung cancer A549 cells. Molecules 2022; 27(13): 4014.
• Chanokbhorn, P., Yenjai, C., Senawong, T., Gulsiri, S., Saenglee, S., Somsakeesit, L., Kumboonma, P. Histone deacetylase inhibitory activity and antiproliferative potential of new [6]-shogaol derivatives. Molecules 2022; 27(10): 3332.
• Kumboonma, P., Saenglee, S., Senawong, T., Phaosiri, C. Discovery of new capsaicin and dihydrocapsaicin derivatives as histone deacetylase inhibitors and molecular docking studies. Organic Communications 2021; 14(2): 133-143.
• Somsakeesit, L., Senawong, T., Kumboonma, P., Saenglee, S., Samankul, A., Senawong, G., Yenjai, C., Phaosiri, C. Influence of side-chain changes on histone deacetylase inhibitory and cytotoxicity activities of curcuminoid derivatives. Bioorganic & Medicinal Chemistry Letters 2020; 30: 127171.
• Kumboonma, P., Senawong T, Saenglee S, Chanokbhorn, P. Histone deacetylase inhibitors and antioxidants from the root of Gluta usitata. Natural Product Communications 2019; 14(12): 1–7.
• Kumboonma, P., Senawong T, Saenglee S, Senawong G, Somsakeesit L, Yenjai C, Chanokbhorn, P. New histone deacetylase inhibitors and anticancer agents from Curcuma longa. Journal of Medicinal Chemistry Research 2019; 28(10): 1773-1782.
• Kumboonma, P., Senawong T, Saenglee S, Chanokbhorn, P. Histone deacetylase inhibitory activity of a biflavone, agathisflavone from Gluta usitata flowers. KKU Science Journal. 2019; 47(2): 225-232.
• Kumboonma, P., Sombatsri S. Antioxidant activities and total phenolic contents from Thai wild fruits. KKU Science Journal. 2019; 47(1): 034-042.
• Kumboonma, P., Senawong T, Saenglee S, Yenjai C, Chanokbhorn, P. New histone deacetylase inhibitors from the twigs of Melanorrhoea usitata. Journal of Medicinal Chemistry Research 2018; 27: 2004-2015. 
• Kumboonma, P., Ruangviriyachai, C., Khansawai, P., Karitpattawan, P., Chanokbhorn, P. New semi-synthetic derivatives of capsaicinoids and their antioxidant activities. Chemistry of Natural Compounds. 2018; 54(3): 550-552. 
• Kumboonma, P., Senawong T, Saenglee S, Yenjai C, Chanokbhorn, P.Identification of phenolic compounds from Zingiber offinale and their derivatives as histone deacetylase inhibitors and antioxidants. Journal of Medicinal Chemistry Research 2017; 26: 650-661.
• Kumboonma, P., Senawong, T., Siriwong, K., Yenjai, C., Phaosiri, C. “Inhibition of capsaicin and dihydrocapsaicin derivatives towards histone deacetylase and molecular docking studies” Songklanakarin J. Sci. Technol. 2016, 38(4), 399–406.
• Senawong, T., Wongphakham, P., Saiwichai, T., Phaosiri, C, Kumboonma P. Histone deacetylase inhibitory activity of hydroxycapsaicin, a synthetic derivative of capsaicin, and its cytotoxic effects against human colon cancer cell lines. Turkish Journal of Biology, 2015; 39, 1-10.
• Somsakeesit, L., Kumboonma, P., Saenglee, S., Senawong, T., Yenjai, C. and Phaosiri, C. Design and evaluation of oleanolic acid derivatives as histone deacetylase inhibitors. The 11^th International Conference on Science, Technology and Innovation for Sustainable Well-Being (STISWB XI), Johor Bahru, Malaysia. 2019, 914-920.
• Kumboonma, P., Phaosiri, C., Yenjai, C., Senawong, T. Saenglee, S. and Siriwong, K. Proceeding in International Congress on Chemical, Biological and Environmental Sciences, Osaka, Japan. 2016, 696-697.
• Khunprathum, C., Kumboonma, P., Karitpattawan, P. and Phaosiri, C. Proceeding in The 6^th International Conference on Natural Products for Health and Beauty (NATPRO6), Khon Kaen, Thailand. 2016, 48-53.
• Khunprathum, C., Kumboonma, P., Karitpattawan, P. and Phaosiri, C. Proceeding in The National and International Graduate Research Conference, Khon Kaen, Thailand. 2016, 308-316.
• Kumboonma, P., Phaosiri, C., Senawong, T., Saiwichai, T., Siriwong, K., Yenjai, C. Synthesis and Pharmacological Evaluation of Capsaicin’s Analogues. Pure and Applied Chemistry International Conference (PACCON 2010). Sunee Grand Hotel and Convention Center, Ubon Ratchathani, Thailand, January 21-23, 2010.
• Kumboonma P., Phaosiri C, Misuna S, Senawong T, Yenjai C. Isolation and Structural Modification of Capsaicin and Dihydrocapsaicin from Capsicum annuum sp. PACCON2009 (Pure and Applied Chemistry International Conference), Naresuan University, Pitsanulok, Thailand 2008; January 14-16, 2009.
• Kumboonma, P., Manosin, N., Khomkhum, S., Phaosiri, C. and Yenjai, C. Proceeding in the 12^th National Graduate Research Conference, Khon Kaen University. 2009, 729-736.
• Kumboonma, P., Phaosiri, C., Misuna, S., Senawong, T. and Yenjai, C. Proceeding in the International Congress for Innovation in Chemistry (PERCH-CIC Congress VI), Pattaya. 2009, 259.

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